Related Experiment Video
Updated: Mar 8, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Enhancing Collaborative Case Diagnoses Through Unified Medical Language System-Based Disambiguation: A Case Study of
Albert Moreira1, Raúl Alonso-Calvo1, Alberto Muñoz2
11 Biomedical Informatics Group, DLSIIS & DIA, ETSIINF, Universidad Politécnica de Madrid , Madrid, Spain .
Background:
During clinical case diagnoses, especially in low-resourced areas, the use of vocabularies within Unified Medical Language System (UMLS) can strengthen discussions between health professionals and, in certain cases, eliminate the need, enabling faster treatment.
Introduction:
This article presents the benefits of using UMLS as a collaborative discussion tool and verifies its impact.
Materials And Methods:
The Sanar system has been improved by UMLS when using text retrieval to extract relevant medical concepts from cases investigated by the user and to provide contextualized searches of related articles. An experiment was conducted, focused on team engagement and discussion of a Zika virus case using Sanar, both with and without UMLS contextualization.
Results:
The use of the tool was measured, and it was determined that the discussion in the group with UMLS support was more complete based on better information and inclusion of more variables. Clinicians involved responded to a questionnaire evaluating the relevance of functions.
Discussion:
From the questionnaire showed that most of the group supported UMLS as important in complex diagnostics; the use of knowledge extraction before discussion is relevant to align knowledge of participants with more variables, such as the Zika virus, and to minimize the need for interaction in widely discussed cases.
Conclusions:
Based on the results obtained with the questionnaire, the use of UMLS provides acceleration in the diagnostic process that precedes interaction with other health professionals through clinical discussion tools. For future work, a mobile version will support offline navigation for locations with limited Internet access.
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