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Sensitivity and specificity of Urdu version of the PHQ-9 to screen depression in patients with coronary artery
Leila Gholizadeh1, Shahzad Ali Khan2, Farnoosh Vahedi1
1a Faculty of Health , University of Technology , 15 Broadway, Ultimo, Sydney2007 , NSW , Australia.
Background:
The Patient Health Questionnaire (PHQ-9) possesses many characteristics of a good screening tool and has the capacity to be used for screening depression in patients with coronary artery disease (CAD).
Aim:
To examine the psychometric properties and criterion validity of the PHQ-9 to screen and detect depression in patients with CAD in Pakistan.
Design:
In this validation study, 150 patients with CAD completed the Urdu version of the PHQ-9. The major depressive episode module of the Mini International Neuropsychiatric Interview (MINI) was used as the gold standard.
Results:
The Urdu version of the PHQ-9 revealed a good internal consistency with Cronbach's alpha of 0.83. Optimal sensitivity (76%) and specificity (76%) were achieved using the cut-off score of PHQ-9 ≥6, with area under the ROC curve of 0.86.
Conclusion:
The Urdu version of the PHQ-9 has acceptable psychometric properties to screen and detect major depression in patients with CAD.
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