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[Endocrinological development in girls during puberty].

T Yanaihara1

  • 1Department of Obstetrics and Gynecology, Showa University School of Medicine, Tokyo.

Nihon Sanka Fujinka Gakkai Zasshi
|August 1, 1989
PubMed
Summary
This summary is machine-generated.

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Puberty involves hormonal shifts, with luteinizing hormone (LH) and follicle-stimulating hormone (FSH) rising before menarche. Menstrual disorders in adolescents often link to abnormal LH and FSH levels.

Area of Science:

  • Endocrinology
  • Reproductive Biology
  • Pediatric Endocrinology

Context:

  • Puberty is a critical developmental stage marked by significant hormonal fluctuations.
  • Understanding these changes is vital for diagnosing and managing adolescent reproductive health issues.

Purpose:

  • To detail endocrinological shifts during female puberty and their relation to sexual development.
  • To investigate the hormonal profiles of adolescent girls experiencing menstrual irregularities.

Summary:

  • Hormonal levels including luteinizing hormone (LH), follicle-stimulating hormone (FSH), and estradiol progressively increase before menarche.
  • Prolactin (PRL) levels show a distinct pattern, rising earlier and then declining before the first menses.
  • Androstenedione, estrone, and dehydroepiandrosterone sulfate (DHA-S) levels differ between sexes, with 5 alpha-androstanediol decreasing pre-menarche.

Related Experiment Videos

  • Correlations were observed between DHA-S, body weight, and breast development, and between testosterone levels and handgrip strength.
  • Functional uterine bleeding and amenorrhea in adolescents are frequently associated with elevated LH and normal FSH levels.
  • Hypothalamic dysfunction in primary and secondary amenorrhea is characterized by the absence of episodic LH secretion.

    • Impact:

    • Provides a comprehensive overview of normal pubertal endocrinology in girls.
    • Offers insights into the pathophysiology of common menstrual disorders in adolescence.
    • Establishes correlations between specific hormones and physical development milestones.
    • Highlights the diagnostic value of hormonal assessments in adolescent gynecological issues.