Related Experiment Video
Updated: Mar 8, 2026
08:41
Assessment of Cardiac Function and Myocardial Morphology Using Small Animal Look-locker Inversion Recovery SALLI MRI in Rats
Published on: July 19, 2013
13.2K
Myocardial T1 and T2 Mapping: Techniques and Clinical Applications
Pan Ki Kim1, Yoo Jin Hong1, Dong Jin Im1
1Department of Radiology and Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Korea.
Korean Journal of Radiology
|January 19, 2017
Summary
Cardiac magnetic resonance (CMR) imaging, using T1 and T2 mapping sequences, quantifies myocardial T1, T2, and ECV values. These metrics serve as vital biomarkers for diagnosing cardiomyopathies and predicting treatment outcomes.
Area of Science:
- Cardiovascular Imaging
- Medical Physics
- Biomarker Discovery
Background:
- Cardiac magnetic resonance (CMR) imaging is crucial for cardiovascular disease assessment.
- Technological advancements are driving innovation in CMR techniques.
- T1 and T2 mapping sequences are increasingly integrated into clinical practice.
Purpose of the Study:
- To review T1 and T2 mapping sequence techniques in CMR.
- To explore the clinical applications of these quantitative mapping sequences.
- To highlight the role of T1, T2, and ECV as biomarkers.
Main Methods:
- Review of current literature on CMR T1 and T2 mapping sequences.
- Analysis of technical aspects of various mapping techniques.
- Synthesis of data on clinical utility and biomarker potential.
Main Results:
- T1 and T2 mapping sequences allow direct quantification of myocardial T1, T2, and ECV.
- These quantitative values are recognized as robust diagnostic biomarkers for cardiomyopathies.
- T1, T2, and ECV values show promise in monitoring treatment response and prognosis.
Conclusions:
- T1 and T2 mapping sequences represent a significant advancement in CMR.
- Quantitative myocardial mapping provides valuable insights beyond traditional imaging.
- These techniques are essential for personalized cardiovascular medicine.
Related Concept Videos
01:24Magnetic Resonance Imaging
10.1K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
10.1K
01:20Imaging Studies for Cardiovascular System II:Types of Echocardiography
750
Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
750
01:28Imaging Studies for Cardiovascular System V: CT
465
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
465
01:27Myocarditis II: Clinical Features and Diagnostic Tests
395
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
395
01:21Imaging Studies for Cardiovascular System IV: CMRI
461
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
461