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Neisseria meningitidis ST11 Complex Isolates Associated with Nongonococcal Urethritis, Indiana, USA, 2015-2016

Evelyn Toh, Dharanesh Gangaiah, Byron E Batteiger

    Emerging Infectious Diseases
    |January 19, 2017
    PubMed

    Insights

    Neisseria meningitidis caused urethritis in men previously suspected of gonorrhea. Genomic analysis suggests a new urethrotropic bacterial strain may be emerging.

    Area of Science:

    • Microbiology
    • Genomics
    • Infectious Diseases

    Background:

    • Neisseria gonorrhoeae is a primary cause of urethritis.
    • Accurate diagnosis of urethritis is crucial for effective treatment.

    Observation:

    • An increase in Neisseria meningitidis-positive urethral cultures was noted in men with suspected gonococcal urethritis.
    • These cases were negative for Neisseria gonorrhoeae.

    Findings:

    • Genomic sequencing was performed on two Neisseria meningitidis isolates from urethritis cases.
    • The isolates belonged to the sequence type 11 complex.

    Implications:

    • These findings suggest a potential emergence of urethrotropic Neisseria meningitidis strains.
    • Further research is needed to understand the clinical significance and transmission of these isolates.
    Keywords:
    NeisseriaNeisseria gonorrhoeaeNeisseria meningitidisbacteriagenomemeningitissexually transmitted diseasesexually transmitted infectionsurethraurethritis

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