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[Cost-effectiveness analysis on colorectal cancer screening program]
1Department of Epidemiology, School of Public Health, Zhejiang University, Hangzhou 310058, China.
Starting colorectal cancer screening at age 50 is more cost-effective. This approach improves the efficiency of screening programs by focusing on older individuals, yielding better health economic outcomes.
Area of Science:
- Health Economics
- Public Health
- Gastroenterology
Background:
- Colorectal cancer (CRC) screening is crucial for early detection and improved patient outcomes.
- Determining the optimal age to initiate CRC screening is essential for maximizing program efficiency and resource allocation.
Purpose of the Study:
- To assess the cost-effectiveness of CRC screening programs across different age demographics from a health economic standpoint.
- To identify age-specific detection rates and cost-effectiveness ratios for CRC screening interventions.
Main Methods:
- Utilized data from a CRC screening program in Jiashan county, Zhejiang province.
- Calculated screening compliance and detection rates (iFOBT positivity, advanced adenoma, CRC, early-stage CRC) by age group.
- Analyzed age-related differences using chi-squared tests and calculated cost-effectiveness ratios.
Main Results:
- Detection rates for iFOBT positivity, advanced adenoma, CRC, and early-stage CRC increased with age.
- Early diagnosis rates showed a negative association with age.
- Excluding younger individuals, the cost-effectiveness of screening individuals aged over 50 improved by 15%-30%.
Conclusions:
- Initiating CRC screening at age 50 is recommended from a health economic perspective.
- Targeting screening at age 50 enhances the overall efficiency of CRC screening programs.
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