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Related Concept Videos

Confocal Fluorescence Microscopy01:16

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Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
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An In-House-Built and Light-Emitting-Diode-Based Photodynamic Therapy Device for Enhancing Verteporfin Cytotoxicity in a 2D Cell Culture Model
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[LED lights in dermatology].

C Noé1, M Pelletier-Aouizerate2, H Cartier3

  • 168, avenue de Verdun, 84300 Cavaillon, France.

Annales De Dermatologie Et De Venereologie
|January 21, 2017
PubMed
Summary
This summary is machine-generated.

Controversial use of light-emitting diodes (LEDs) in dermatology stems from device variability and conflicting evidence. This review clarifies the therapeutic value of specific LED wavelengths for various skin conditions.

Keywords:
AcneAcnéCicatrisationDermatologieDermatologyLEDRajeunissementRejuvenationWound healing

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Area of Science:

  • Dermatology
  • Photomedicine
  • Biophysics

Background:

  • The application of light-emitting diodes (LEDs) in dermatology is debated due to a lack of understanding regarding device physicochemical properties.
  • Discrepancies exist between in vitro/cellular studies and clinical outcomes for indications like rejuvenation, acne, and wound healing.

Purpose of the Study:

  • To provide a factual overview of therapeutic LED devices used in dermatology.
  • To offer a nuanced perspective on the efficacy of LED technology for various dermatological conditions.

Main Methods:

  • Review of existing literature on LED devices in dermatology.
  • Analysis of physicochemical properties and wavelength-specific effects of therapeutic LEDs.
  • Evaluation of evidence for different dermatological applications.

Main Results:

  • Therapeutic LEDs emit wavelengths from UV to near-infrared (247-1300 nm), with only specific bands showing proven value.
  • Clinical results for conditions such as acne, wound healing, and inflammatory processes are often discordant.
  • Variability in LED device characteristics complicates direct comparisons and understanding of efficacy.

Conclusions:

  • A clearer understanding of LED device properties and specific wavelength efficacy is needed.
  • Nuanced interpretation of current evidence suggests selective applications for LED therapy in dermatology.
  • Further research is warranted to reconcile in vitro findings with clinical outcomes for broader LED adoption.