Assessment of a Clinical Pharmacy Activity in a Pediatric Inpatient Department in Cote D'ivoire
Danho Pascal Abrogoua1, César Pacôme Békégnran2, Bi Marius Gro3
1Department of Clinical Pharmacy and Therapeutics, Faculty of Pharmaceutical and Biological Sciences, Félix Houphouët-Boigny University, Abidjan, Cote d'Ivoire; Department of Clinical Pharmacology, Teaching Hospital of Cocody, Abidjan, Cote d'Ivoire.
Insights
Pharmaceutical interventions in pediatric care significantly improve patient management. These interventions were highly accepted by physicians and demonstrated substantial clinical impact, preventing adverse drug events.
Area of Science:
- Clinical Pharmacy
- Pediatric Medicine
- Drug Safety
Background:
- Clinical pharmacy services enhance patient care and economic outcomes in pediatric inpatient settings.
- Effective pharmaceutical interventions are crucial for optimizing pediatric treatment plans.
Purpose of the Study:
- To evaluate the significance and impact of pharmaceutical interventions (PIs) in a pediatric hospital in Abidjan, Cote d'Ivoire.
- To assess the relevance of PIs by analyzing physician acceptance and clinical impact.
Main Methods:
- A cross-sectional, descriptive study was conducted from February to September 2014.
- Drug-related problems (DRPs) and PIs were classified using the French Society of Clinical Pharmacy criteria.
- PI relevance was determined by physician acceptance rates and assessed clinical impact scores (PI0-PI3).
Main Results:
- 116 PIs were performed, primarily during patient record analysis (68.1%).
- Key DRPs included noncompliance, overdose, and underdosing.
- PIs focused on dose adjustments, administration accuracy, and therapeutic choices, with a high acceptance rate (94.8%).
- Most PIs had significant (67.3%) or very significant (16.4%) clinical impact.
Conclusions:
- Pharmaceutical interventions in this pediatric unit were highly relevant and effective.
- PIs contributed to optimizing therapy and preventing iatrogenic events in hospitalized children.
Background:
Clinical pharmacy activities in a pediatric inpatient department help to improve the management of patients clinically and economically.
Objective:
To assess the relevance of pharmaceutical interventions (PIs) in a pediatric inpatient department in Abidjan (Cote d'Ivoire).
Materials And Methods:
We carried out a cross-sectional, descriptive study from February to September 2014. The information collected was classified according to the classification of drug-related problems (DRPs) and PIs of the French Society of Clinical Pharmacy. The score assigned to each PI varied from PI0 (without direct clinical impact) to PI3 (vital clinical impact) as the importance of the potential clinical impact of the DRP was correlated to the severity of clinical consequences avoided by the PI. The relevance of PIs was assessed by their rate of acceptance by physicians and by the analysis of their clinical impact.
Results:
A total of 116 PIs were performed with 31% performed during medical rounds, 68.1% during patients' records analysis, and 0.1% on patient's admission. The main DRPs were related to noncompliance with recommendations (24.1%), overdose (21.1%), and underdosing (13.8%). The most important PIs were dose adjustment (31.8%), accuracy of drugs administration modalities (29.3%), and proposals of therapeutic choice (27.6%). The acceptance rate of PIs was highly significant (94.8%). The majority of PIs (67.3%) was assessed as having a significant clinical impact (PI1) and 16.4% of PIs as very significant clinical impact (PI2). A single PI (0.9%) was found with vital clinical impact.
Conclusion:
PIs performed were relevant and contributed to the therapeutic optimization and the prevention of iatrogenic events in pediatric inpatients.
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