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Retroperitoneal unicentric Castleman's disease: A case report.

Nihed Abdessayed¹, Ahlem Bdioui¹, Houssem Ammar²

¹Department of Pathology, Farhat Hached University Hospital, Sousse, Tunisie; Research Lab: Transfer in Technology in Anatomic Pathology, LR12SP08, Tunisie.

International Journal of Surgery Case Reports

|January 21, 2017

Summary

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Castleman's disease (CD) is a rare cause of retroperitoneal masses. This case highlights the hyaline-vascular type of unicentric CD in the peripancreatic region, successfully treated with surgical excision.

Area of Science:

Gastroenterology
Surgical Oncology
Pathology

Background:

Castleman's disease (CD) is a rare lymphoproliferative disorder.
It typically presents as angio-follicular lymph node hyperplasia.
Unicentric CD in the peripancreatic region is exceptionally rare.

Purpose of the Study:

To report a rare case of unicentric Castleman's disease.
To discuss its presentation, diagnosis, and management.
To highlight diagnostic challenges in differentiating it from pancreatic neoplasms.

Main Methods:

Case report of a 34-year-old female with epigastric pain.
Abdominal imaging revealing a retroperitoneal mass suspected to be a neuroendocrine tumor.
Complete surgical excision and subsequent histopathological examination.

Keywords:

Case report Castleman’s disease Lymph node hyperplasia Retroperitoneum

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Main Results:

Histopathology confirmed localized hyaline-vascular type of Castleman's disease.
The patient experienced an uneventful recovery post-surgery.
Preoperative differentiation from pancreatic neoplasm was challenging.

Conclusions:

Unicentric CD can mimic pancreatic neoplasms, posing diagnostic difficulties.
Surgical excision is the standard therapy for localized CD.
Preoperative biopsy may aid in avoiding unnecessary extensive surgery for this benign condition.