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Value of Ultrasonographic Features for Assessing Malignant Potential of Complex Cystic Breast Lesions
Jin-Peng Yao1, Yu-Zhi Hao1, Qing Chang1
1Department of Pathology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Objectives:
To assess the value of ultrasonography (US) features for determining the malignant potential of complex cystic lesions.
Methods:
Seventy-nine complex cystic lesions were reviewed retrospectively. They were classified into four types according to US features in type I, the masses have a thick outer wall, thick internal septa, or both; in type II, the masses are an intracystic type with one or more discrete solid mural lesions within a cyst; in type III, the masses contain mixed cystic and solid components and are at least 50% cystic portion in a mass; in type IV, there are predominantly (at least 50%) solid masses with eccentric or central cystic foci. Positive predictive values were calculated for all types.
Results:
The frequency of malignancy was higher among type III and IV lesions than among the other two types. Lesions with a diameter greater than or equal to 20 mm, margins not circumscribed, resistance index greater than or equal to 0.7, and axillary abnormal nodes had a high probability of malignancy.
Conclusions:
US is an important adjunct to evaluate the malignant potential of complex cystic lesions.
