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Updated: Mar 8, 2026

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 25, 2016
Juvenile systemic lupus erythematosus (jSLE): Auditory pathway affection in relation to disease activity
M A Kotait1, H H Abd Elnabi2, T A Gabr1
1Audiology Unit, Otolaryngology Head and Neck Surgery Department, Faculty of Medicine, Tanta University, Egypt.
Background:
Juvenile Systemic lupus erythematosus (jSLE) is an autoimmune disease with the potential to affect a variety of organs in children or adolescents. jSLE is characterized by its severity and more widespread organ involvement specially central nervous system.
Objectives:
To evaluate auditory processing and cognitive functions in children and adolescents with SLE taking into consideration the disease severity.
Methods:
This work included 40 normal hearing pediatric patients diagnosed as SLE (23 with active disease and 17 with inactive disease) and a control group included 30 matched healthy children. The methodology included basic audiologic evaluation, mismatch negativity (MMN) in response to speech and tone stimuli and memory tests.
Results:
Children with jSLE showed impaired hearing thresholds. They also showed impaired MMN recording in response to speech or tone stimuli with impaired memory subtests.
Conclusions:
Peripheral and central auditory systems are affected in jSLE. This affection is worse with active disease.
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