Related Experiment Video
Updated: Oct 3, 2025

Semi-Automated Analysis of Peak Amplitude and Latency for Auditory Brainstem Response Waveforms Using R
Published on: December 9, 2022
Tinnitus: impact on patients in relation to audiological findings
T A Gabr1, H F Alshabory1, M A Kotait2
1Audiovestibular Medicine Unit, Otolaryngology Department, Faculty of Medicine, Kafrelsheikh University, Kafr El Sheikh, Egypt.
Objective:
Tinnitus is a common auditory disorder in which patients experience noise in the absence of an external source. It is a consequence of irreversible cochlear damage. This study examined the distortion product otoacoustic emissions and P300 components of event-related potentials.
Method:
This study included a control group of 25 normal-hearing adults not complaining of tinnitus and a study group that consisted of 45 normal-hearing adults complaining of tinnitus. Measures included patient history, basic audiological evaluation, the Arabic version of Tinnitus Handicap Inventory, distortion product otoacoustic emissions testing and P300 recording.
Results:
The study group showed significantly higher hearing thresholds at all frequencies as well as delayed latencies and reduced amplitude of P300. The Tinnitus Handicap Inventory showed mean scores of 35.2 ± 16.9, and the distortion product gram showed higher amplitudes in the control group.
Conclusion:
Patients with tinnitus might have neural dysfunction at either peripheral or central levels of the auditory pathway.
Related Concept Videos
Hearing
Perceiving Loudness, Pitch, and Location
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by...
Perception of Sound Waves
The pitch of a sound depends on the frequency and the pressure amplitude of the source. Two sounds of the same...

