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Distortion Product Otoacoustic Emissions (DPOAEs) In Tinnitus Patients
Hend F Alshabory1, Takwa A Gabr1, Mona A Kotait2
1Audiovestibular Medicine Unit, Otolaryngology Department, Faculty of Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt.
International Archives of Otorhinolaryngology
|January 31, 2022
Summary
Tinnitus patients with normal hearing exhibit reduced distortion product otoacoustic emissions (DPOAEs), indicating potential cochlear neural dysfunction. This study compared DPOAEs in tinnitus sufferers versus controls, finding significant differences in auditory function.
Area of Science:
- Audiology
- Neuroscience
- Otoacoustic Emissions
Background:
- Tinnitus is the perception of sound without external stimulation, often linked to cochlear damage.
- Distortion product otoacoustic emissions (DPOAEs) reflect cochlear outer hair cell function.
Purpose of the Study:
- To investigate DPOAEs in normal-hearing tinnitus patients compared to controls.
- To explore correlations between DPOAE measurements and tinnitus complaints.
Main Methods:
- Included 80 participants: 50 with tinnitus and 30 controls, all with normal hearing.
- Utilized audiological history, otoscopic examination, basic audiological evaluation, DP-grams, and DPOAE input/output functions.
Main Results:
- Tinnitus patients showed significantly higher hearing thresholds across frequencies.
- DP-grams and DPOAE input/output functions revealed lower amplitudes in tinnitus patients.
- The slope of the DPOAE input/output function was steeper in tinnitus cases.
Conclusions:
- Reduced DPOAE levels and altered DP-I/O functions suggest neural dysfunction in the cochlea of tinnitus patients.
- These findings highlight DPOAEs as a potential biomarker for subclinical cochlear changes in tinnitus.
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