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Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
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Potential relationship between periodontal diseases and eye diseases
Z A D Pockpa1, X Struillou2, N T Coulibaly3
1UIC Odontology, CHU NANTES, LIOAD Inserm U791, Faculty of Dental Surgery, University of Nantes, 1 place Alexis Ricordeau, 44200 Nantes, France.
Medical Hypotheses
|January 24, 2017
Summary
Periodontal diseases, an oral inflammatory condition, are linked to various systemic diseases. Emerging evidence suggests a connection between these gum diseases and certain eye disorders, though mechanisms require further study.
Area of Science:
- Oral Health and Systemic Diseases
- Ophthalmology
- Immunology
Background:
- Periodontal diseases are inflammatory conditions caused by oral bacteria, leading to tooth support structure destruction.
- Periodontal diseases are associated with systemic conditions like diabetes, cardiovascular disease, and rheumatoid arthritis.
- Certain eye diseases share links with systemic inflammatory conditions.
Purpose of the Study:
- To investigate the potential association between periodontal diseases and eye diseases.
- To explore possible biological mechanisms linking periodontal and ocular health.
Main Methods:
- Literature review of studies reporting associations between periodontal diseases and eye disorders.
- Analysis of potential shared etiological factors and immune pathways.
Main Results:
- Several studies indicate a correlation between the presence of periodontal diseases and various eye disorders.
- The precise biological mechanisms underlying this association remain unclear.
- Involvement of the innate immune response, shared risk factors, and changes in choroidal thickness are proposed hypotheses.
Conclusions:
- Periodontal diseases may be associated with certain eye diseases.
- Further research is needed to elucidate the specific mechanisms driving this relationship.
- Investigating shared inflammatory pathways and risk factors could provide insights into preventing both conditions.
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