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Updated: Mar 8, 2026
Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells
Published on: March 16, 2017
Ratiometric SERS imaging and selective biosensing of nitric oxide in live cells based on trisoctahedral gold
1Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, School of Chemistry and Molecular Engineering, East China Normal University, Dongchuan Road 500, Shanghai 200241, P. R. China. ytian@chem.ecnu.edu.cn.
Abstract:
Herein, a ratiometric SERS probe was created for monitoring nitric oxide (NO) by designing a novel molecule, 3,4-diaminobenzene-thiol, and immobilizing this molecule onto trisoctahedral gold nanostructures with superior SERS capability. The established probe possessed good selectivity and biocompatibility, high sensitivity and accuracy, thus enabling imaging and biosensing of NO in live cells.
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