Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Beyond Conventional Sleep Parameters: Circadian Rhythm Disruption in Adolescents with Juvenile Myoclonic Epilepsy: An Actigraphy Study.

Journal of clinical medicine·2026

Same author

A Rare Genetic Disorder Presenting with Neuropsychiatric Involvement and Drug-Resistant Epilepsy: The First Adult Patient with Adenylosuccinate Lyase Deficiency in Türkiye.

Noro psikiyatri arsivi·2026

Same author

The contribution of trapezius and sternocleidomastoideus motor evoked potentials in the diagnosis of Amyotrophic lateral sclerosis.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026

Same author

Cytokine Profiles in Myasthenia Gravis Subgroups and the Lack of Any Effect of Immunosuppression.

Muscle & nerve·2026

Same author

Effect of CXCR5, PD-1 and ICOS on B-cell responses and relevance to myasthenia gravis.

Clinical & translational immunology·2026

Same author

Sexual dysfunction is underrecognized in patients with migraine: A systematic review and meta-analysis.

Headache·2026

Search research articles

Related Experiment Video

Updated: Mar 8, 2026

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion

Published on: November 12, 2020

[A HaNDL case with papilledema mimicking transient ischemic attack].

İpek Güngör¹, Arman Çakar, Elif Kocasoy Orhan

¹Department of Neurology, Istanbul Faculty of Medicine, Istanbul, Turkey. dripekgngr@gmail.com.

Agri : Agri (Algoloji) Dernegi'Nin Yayin Organidir = the Journal of the Turkish Society of Algology

|January 24, 2017

Summary

Transient headache and neurologic deficits with cerebrospinal fluid lymphocytosis (HaNDL) is a rare, benign syndrome. Early CSF examination is key for diagnosing HaNDL, which can mimic serious conditions.

More Related Videos

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia

Published on: November 15, 2024

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

Related Experiment Videos

Last Updated: Mar 8, 2026

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion

Published on: November 12, 2020

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia

A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia

Published on: November 15, 2024

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

Area of Science:

Neurology
Neuroimmunology

Background:

Transient headache and neurologic deficits with cerebrospinal fluid lymphocytosis (HaNDL) is a rare, benign, self-limiting neurological syndrome.
Its pathogenesis is not fully understood, but autoimmunity is suspected.
HaNDL presents with diverse neurological symptoms that can mimic more severe conditions.

Observation:

A case of HaNDL is presented, initially mimicking a transient ischemic attack (TIA).
The patient experienced temporary, recurrent neurological deficits.
Cerebrospinal fluid (CSF) analysis revealed lymphocytosis, and papilledema was present with normal CSF pressure.

Findings:

CSF examination is diagnostically valuable for HaNDL.
The syndrome's symptomatology can be mistaken for other serious neurological diseases.
Autoimmunity is a leading hypothesis for HaNDL's cause.

Implications:

Recognizing HaNDL is crucial to avoid misdiagnosis and unnecessary aggressive treatments.
Further research into HaNDL's ethiopathogenesis may reveal targeted treatments.
Understanding HaNDL improves patient outcomes by enabling prompt and accurate diagnosis.