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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
Acrodermatitis Enteropathica Type II
Insights
A 5-month-old infant with skin lesions showed low serum zinc levels. Oral zinc therapy successfully treated the condition, resolving symptoms after weaning even without continued supplementation.
Area of Science:
- Pediatric Dermatology
- Nutritional Deficiencies
Background:
- Zinc deficiency can manifest with various dermatological symptoms in infants.
- Early diagnosis and intervention are crucial for managing nutritional disorders.
Observation:
- A 5 1/2-month-old male infant presented with a month-long history of vesiculopustular cutaneous lesions, erythema, erosions, scaling, and crusting.
- Lesions were predominantly observed in the peri-orificial areas.
- The infant's mother had normal serum zinc levels and no signs of deficiency.
Findings:
- The infant exhibited low serum zinc levels, contrasting with his mother's normal levels.
- Oral zinc therapy led to a complete resolution of the infant's cutaneous lesions and associated symptoms.
- Symptoms did not recur after the infant was weaned, even without ongoing zinc supplementation.
Implications:
- This case highlights the importance of considering zinc deficiency in infants presenting with unexplained dermatological conditions.
- Prompt zinc supplementation can effectively treat zinc-responsive dermatoses in infants.
- The resolution of symptoms post-weaning suggests a potential link between dietary intake and zinc status in this infant.
Abstract:
A 5 1/2 month old male had vesiculopustular cutaneous lesions along with erythema, erosions, scaling and crusting particularly prominent in the peri - orificial areas for the last 1 month. He was the first child of his mother who had no sign of zinc deficiency. Serum zin level was normal in the mother, but low in the baby. Oral zinc therapy cured the baby. After weaning the baby was disease free even without oral zinc.
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