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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
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Acrodermatitis Enteropathica Type II.

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    This summary is machine-generated.

    A 5-month-old infant with skin lesions showed low serum zinc levels. Oral zinc therapy successfully treated the condition, resolving symptoms after weaning even without continued supplementation.

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    Area of Science:

    • Pediatric Dermatology
    • Nutritional Deficiencies

    Background:

    • Zinc deficiency can manifest with various dermatological symptoms in infants.
    • Early diagnosis and intervention are crucial for managing nutritional disorders.

    Observation:

    • A 5 1/2-month-old male infant presented with a month-long history of vesiculopustular cutaneous lesions, erythema, erosions, scaling, and crusting.
    • Lesions were predominantly observed in the peri-orificial areas.
    • The infant's mother had normal serum zinc levels and no signs of deficiency.

    Findings:

    • The infant exhibited low serum zinc levels, contrasting with his mother's normal levels.
    • Oral zinc therapy led to a complete resolution of the infant's cutaneous lesions and associated symptoms.
    • Symptoms did not recur after the infant was weaned, even without ongoing zinc supplementation.

    Implications:

    • This case highlights the importance of considering zinc deficiency in infants presenting with unexplained dermatological conditions.
    • Prompt zinc supplementation can effectively treat zinc-responsive dermatoses in infants.
    • The resolution of symptoms post-weaning suggests a potential link between dietary intake and zinc status in this infant.