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Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells
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Published on: April 4, 2016

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Combinatorics of Tandem Duplication Random Loss Mutations on Circular Genomes

Tom Hartmann, An-Chiang Chu, Martin Middendorf

    IEEE/ACM Transactions on Computational Biology and Bioinformatics
    |January 24, 2017
    PubMed
    Summary

    Tandem duplication random loss (TDRL) operations rearrange metazoan mitochondrial genomes. This study analyzes TDRL combinatorics on circular genomes, establishing theoretical results with practical relevance for animal mitochondrial gene orders.

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