Related Experiment Video
Updated: Aug 7, 2026

Handheld Metal Detector Screening for Metallic Foreign Body Ingestion in Children
Published on: September 11, 2018
Recurrent poisonings among paediatric poisoning victims
T L Litovitz1, S L Flagler, A S Manoguerra
1National Capital Poison Center, Georgetown University Hospital, Washington, D.C.
Insights
Children under six frequently re-ingest poisons, with ingestions of drugs increasing with age. Repeat poison exposures show a tendency to involve similar substances, highlighting the need for targeted prevention strategies.
Area of Science:
- Toxicology
- Pediatric Health
- Public Health
Background:
- Poison ingestions are a significant concern in young children.
- Understanding patterns of repeat ingestions is crucial for prevention.
Purpose of the Study:
- To determine the incidence of poison exposures in children under six.
- To analyze factors influencing repeat poison ingestions, including age and substance type.
Main Methods:
- Analysis of 1943 potentially toxic ingestions reported to three diverse poison centers.
- Examination of demographic data, focusing on age and prior exposure history.
- Statistical analysis of substance types ingested in relation to age and repeat exposure.
Main Results:
- 30.1% of children experienced prior poison exposures, with higher rates in older children (3-5 years).
- Drug ingestions increased significantly with age, while household product ingestions decreased.
- A statistically significant tendency for repeat ingestions of similar poison types was observed.
Conclusions:
- Age is a critical factor influencing the type of substance ingested by children.
- Children exhibit a propensity to re-ingest similar toxic substances, indicating a need for tailored interventions.
- Findings underscore the importance of age-specific poison prevention education and targeted strategies for repeat offenders.
Abstract:
A study of 1943 potentially toxic ingestions occurring in children under 6 years of age was conducted by 3 geographically and demographically diverse poison centres to determine the incidence of exposures to poison. Of the total group, 30.1% indicated that the child had experienced a prior poison exposure (12.0% in children under 1 year of age, and 41.3% of children between the ages of 3 and 5 years). Most repeaters (68.9%) experienced only 1 prior ingestion (range 1 to 15). Two prior ingestions were reported in 17.6% of repeaters; 3 prior ingestions in 4.4%. A profound effect of age on type of substance ingested was observed, with drugs accounting for 11.0% of ingestions in children under the age of 1 year, 23.2% in 1-year-old, and 49.9% in 2- to 5-year-old. A corresponding age-related decline in ingestions of household and personal care products was also noted. Although less marked than the age effect, a statistically significant propensity to re-ingest similar types of poisons was observed. Among repeaters, those with a prior ingestion of a drug subsequently ingested another drug 1.49 times more frequently than expected. A similar trend was observed with products (1.24 times more frequently) and plants (2.00 times more frequently).
More Related Videos
08:53Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
Published on: December 4, 2020
16:02Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation
Published on: February 10, 2023
Related Concept Videos
Types of Toxins
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Prevention of Further Absorption of Poison
Anticholinesterase Agents: Poisoning and Treatment
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is slower than the...
Enhanced Elimination of Poison
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...
Pharmaceutical Poisoning: Potential Scenarios
Pharmaceutical Poisoning: Treatment Strategies