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The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels

Christina Valkova1, Lutz Liebmann2, Andreas Krämer1

  • 1Leibniz Institut für Alternsforschung-Fritz Lipmann Institut, 07743 Jena, Germany.

Scientific Reports
|January 25, 2017
PubMed
Summary

The sorting receptor Rer1 is crucial for Purkinje cell function. Loss of Rer1 impairs voltage-gated sodium channels, leading to age-dependent motor deficits and Purkinje cell degeneration.

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