The Postsynthetic Renaissance in Porous Solids

Area of Science:

• Materials Science
• Solid-State Chemistry
• Covalent Chemistry

Background:

• Metal-organic frameworks (MOFs) have emerged as a significant research area in chemistry.
• MOFs extend covalent chemistry from discrete molecules to extended structures.
• They serve as scaffolds for heterogeneous organic transformations in the solid state.

Purpose of the Study:

• To explore the development of MOFs as platforms for chemical transformations.
• To highlight the concept of the "postsynthetic renaissance" in MOF chemistry.
• To showcase methods for creating novel crystalline, porous materials.

Main Methods:

• Utilizing MOFs as a scaffold for heterogeneous organic transformations.
• Employing single-crystal-to-single-crystal transformations for material modification.
• Applying various postsynthetic methods including modification, deprotection, exchange, insertion, and polymerization.

Main Results:

• Demonstration of MOFs as versatile platforms for solid-state chemical reactions.
• Successful implementation of the "postsynthetic renaissance" for MOF derivatization.
• Creation of crystalline, porous solids with enhanced complexity and functionality.

Conclusions:

• MOFs offer unique opportunities for designing and synthesizing advanced materials.
• Postsynthetic strategies enable precise control over MOF structure and properties.
• The field of MOFs continues to expand, offering novel functionalities through chemical transformations.