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Synthesis of Aptamer-PEI-g-PEG Modified Gold Nanoparticles Loaded with Doxorubicin for Targeted Drug Delivery
Published on: June 23, 2020
[Polymer nanoparticles for the delivery of anticancer drug]
Julien Nicolas1, Patrick Couvreur1
1Institut Galien Paris-Sud, UMR CNRS 8612, Université Paris-Sud, Faculté de Pharmacie, 5, rue Jean-Baptiste Clément, F-92296 Châtenay-Malabry Cedex, France.
Abstract:
Nanocarriers based on polymers are currently attracting much attention to perform efficient drug delivery, especially in cancer therapy. Over the last decades, different kinds of polymer nanoparticulate systems have been developed (e.g., simple, stealth, targeted, stimuli-responsive and prodrug) to propose novel, better and safer cancer therapies. This article will give a brief overview of the different classes of polymer nanoparticles that have been reported and discuss some key achievements deriving from their use in the field of cancer therapy.
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