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Modelling the occurrence and pathology of Alzheimer's disease
J A Hardy1, A M Goate, M J Owen
1Department of Biochemistry, St. Mary's Hospital Medical School, London.
Neurobiology of Aging
|September 1, 1989
Abstract:
Our work has confirmed that of St. George-Hyslop and colleagues, suggesting FAD linkage to the short arm of chromosome 21 in outbred families with a presenile onset of the disease. Future genetic studies should help clarify the current apparent discrepancies between certain laboratories and ultimately lead to a better understanding of the variables which predispose individuals to the disease.