Ion Pairing Chromatography
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Critical Reviews in Analytical Chemistry
|January 27, 2017
Summary
This review details advances in ion-pair chromatography (IPC), focusing on theoretical models for solute retention and practical applications over the last decade. It highlights IPC
Area of Science:
- Analytical Chemistry
- Separation Science
Background:
- Ion-pair chromatography (IPC) is a powerful separation technique.
- Understanding the theoretical basis of IPC is crucial for optimizing separations.
- Recent advancements have expanded its applicability.
Purpose of the Study:
- To review the current state of ion-pair chromatography (IPC).
- To emphasize theoretical modeling of solute retention behavior.
- To outline the progression of IPC applications over the past decade.
Main Methods:
- Review of theoretical models (stoichiometric and thermodynamic) for IPC retention.
- Analysis of recent applications of IPC in various fields.
- Discussion of detection and hyphenation techniques in IPC.
Main Results:
- Thermodynamic models provide a detailed understanding of IPC interactions.
- IPC has been successfully applied to diverse analyses, including chiral compounds.
- The practical potential of IPC as a separation strategy is significant.
Conclusions:
- IPC is a well-understood and versatile separation technique.
- Theoretical advancements have enhanced the practical utility of IPC.
- Further research into non-separative aims of IPC is warranted.
Keywords:
Ion-pairingapplicationscomparisondetectionexperimental factorshyphenationnon-separative aimsretention modellingMore Related Videos
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