Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Healthcare Associated Infections II: Preventive Measures

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Action Plan to Better Approximate Reality in Cost-Effectiveness Analyses.

Applied health economics and health policy·2026

Same author

Access To Community Pharmacies Associated With Reduced Racial And Ethnic Disparities In Use Of Prescription Drugs, 2010-19.

Health affairs (Project Hope)·2026

Same author

Association of 340B entity eligibility with changes in hospital financial performance.

Health affairs scholar·2026

Same author

Rural-Urban Differences in Coverage Gains Under Continuous Postpartum Medicaid Eligibility.

Women's health issues : official publication of the Jacobs Institute of Women's Health·2026

Same author

Principles and practices for successful gene therapy innovative contracting: Insights from a multistakeholder convening.

Journal of managed care & specialty pharmacy·2026

Same author

Estimating True Patient Cost-Sharing Burden: Multi-Payer Claim Reconciliation in an All-Payer Claims Database.

Medical care research and review : MCRR·2026

Search research articles

Related Experiment Video

Updated: Mar 8, 2026

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria

Published on: May 8, 2013

Screening test recommendations for methicillin-resistant Staphylococcus aureus surveillance practices: A

Melanie D Whittington¹, Donna J Curtis², Adam J Atherly³

¹Department of Health Systems, Management, and Policy, University of Colorado Anschutz Medical Campus, Aurora, CO; Department of Clinical Pharmacy, University of Colorado Anschutz Medical Campus, Aurora, CO.

American Journal of Infection Control

|January 28, 2017

Summary

For methicillin-resistant Staphylococcus aureus (MRSA) surveillance in ICUs, polymerase chain reaction screening minimizes costs for universal isolation, while 24-hour chromogenic agar testing is cost-effective for targeted isolation of MRSA-positive patients.

Keywords:

Cost-effectiveness Infection control Isolation Surveillance

More Related Videos

Multiplex PCR Assay for Typing of Staphylococcal Cassette Chromosome Mec Types I to V in Methicillin-resistant Staphylococcus aureus

Multiplex PCR Assay for Typing of Staphylococcal Cassette Chromosome Mec Types I to V in Methicillin-resistant Staphylococcus aureus

Published on: September 5, 2013

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA

Published on: February 9, 2011

Related Experiment Videos

Last Updated: Mar 8, 2026

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria

Published on: May 8, 2013

Multiplex PCR Assay for Typing of Staphylococcal Cassette Chromosome Mec Types I to V in Methicillin-resistant Staphylococcus aureus

Multiplex PCR Assay for Typing of Staphylococcal Cassette Chromosome Mec Types I to V in Methicillin-resistant Staphylococcus aureus

Published on: September 5, 2013

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA

Published on: February 9, 2011

Area of Science:

Infection Control and Hospital Epidemiology
Clinical Microbiology
Health Economics

Background:

Intensive care units (ICUs) use surveillance and isolation precautions to mitigate methicillin-resistant Staphylococcus aureus (MRSA) infections.
Common strategies include universal preemptive isolation or targeted isolation of MRSA-positive patients.

Purpose of the Study:

To compare the total costs of universal preemptive isolation versus targeted isolation strategies for MRSA surveillance in ICUs.
To identify the most cost-effective screening test for each isolation approach.

Main Methods:

Decision analysis was employed to calculate total costs for different surveillance and screening scenarios.
Probabilistic sensitivity analysis was conducted to assess the impact of input variations on total costs.

Main Results:

Universal preemptive isolation costs were minimized with polymerase chain reaction (PCR) screening ($82.51/patient), compared to conventional culture ($207.60 more/patient).
Targeted isolation costs were minimized with 24-hour chromogenic agar testing ($8.54/patient), compared to PCR ($22.41 more/patient).

Conclusions:

For universal preemptive isolation, PCR screening is recommended to minimize total costs by reducing inappropriate isolation expenses.
For targeted isolation, 24-hour chromogenic agar testing is recommended to minimize overall costs.