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Related Concept Videos

Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

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The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
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Acute Pancreatitis I: Introduction01:27

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Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
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Pericarditis I: Introduction01:22

Pericarditis I: Introduction

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Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
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Pneumonia I: Introduction01:30

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Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
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Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

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Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
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Pneumonia II: Pathophysiology01:29

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The pathophysiology of pneumonia involves the following steps:
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Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection
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Panniculitis: A summary.

Mark R Wick1

  • 1Section of Dermatopathology,Dermatopathology, Division of Surgical Pathology & Cytopathology, University of Virginia Medical Center, Charlottesville, VA, USA.

Seminars in Diagnostic Pathology
|January 29, 2017
PubMed
Summary
This summary is machine-generated.

This review simplifies panniculitis diagnosis by classifying subcutaneous inflammatory diseases. It categorizes conditions based on septal or lobular involvement and the presence or absence of vasculitis for clearer understanding.

Keywords:
Alpha-1-antitrypsin deficiencyBehçet diseaseCold panniculitisDermatomyositisEosinophilic panniculitisErythema induratum, pancreatogenic panniculitisErythema nodosumFactitial panniculitisInfectious panniculitisLipodermatosclerosisLupus erythematosusMorphea profundaNecrobiosis lipoidicaPannniculitisPolyarteritis nodosaPost-irradiation panniculitisSclerema neonatorumSubcutaneous fat necrosis of the newbornSweet syndromeVasculitis

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Area of Science:

  • Dermatopathology
  • Histopathology
  • Inflammatory diseases of the subcutis

Background:

  • Panniculitis diagnosis can be challenging for pathologists.
  • A systematic classification of subcutaneous inflammatory diseases is needed.

Purpose of the Study:

  • To present a systematic approach to diagnosing panniculitis.
  • To classify inflammatory diseases of the subcutis based on histopathological features.

Main Methods:

  • Review of inflammatory diseases of the subcutis.
  • Classification based on location (fibrovascular septa vs. adipose lobules).
  • Classification based on presence or absence of vasculitis.

Main Results:

  • Septocentric non-vasculitis panniculitides include erythema nodosum, drug-induced panniculitis, lipodermatosclerosis, post-irradiation panniculitis, morphea profunda, and necrobiosis lipodica profunda.
  • Septocentric vasculitic panniculitides include polyarteritis nodosa and Behçet's disease.
  • Lobulocentric non-vasculitis panniculitides include pancreatogenic panniculitis, alpha-1-antitrypsin deficiency panniculitis, lupus erythematosus/dermatomyositis-associated panniculitis, Sweet syndrome, eosinophilic panniculitis, factitial panniculitis, cold panniculitis, corticosteroid injection-induced panniculitis, lipomembranous panniculitis, sclerema neonatorum, subcutaneous fat necrosis, and Rosai-Dorfman disease.
  • Lobulocentric vasculitic panniculitides include erythema induratum and infectious panniculitis.

Conclusions:

  • A classification system based on location and vasculitis aids in diagnosing panniculitis.
  • Understanding these histological features is crucial for accurate diagnosis.
  • This systematic approach simplifies the diagnostic process for complex panniculitis cases.