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Posterior Reversible Encephalopathy Syndrome: A Review
Jai Shankar1, Jillian Banfield1
1Department of Diagnostic Imaging, QE II Health Sciences Centre, Halifax, Nova Scotia, Canada.
Summary
Posterior reversible encephalopathy syndrome (PRES) can be diagnosed by radiologists. Prompt recognition of PRES imaging findings leads to complete reversal, while delayed diagnosis can result in severe outcomes.
Area of Science:
- Neurology
- Radiology
- Medical Imaging
Background:
- Posterior reversible encephalopathy syndrome (PRES) is a neurological condition often initially identified by radiologists.
- PRES is linked to various conditions, including eclampsia, hypertension, and immunosuppressive therapies.
- Awareness of PRES imaging findings is crucial for timely diagnosis.
Purpose of the Study:
- To review the characteristic imaging findings of PRES on CT and MRI.
- To emphasize the importance of early diagnosis and treatment of PRES.
- To highlight the potential for complete reversal of PRES with prompt intervention.
Main Methods:
- Review of computed tomography (CT) and magnetic resonance imaging (MRI) findings in PRES patients.
- Analysis of the association between PRES and common clinical entities.
- Discussion of the clinical spectrum and outcomes of PRES.
Main Results:
- PRES exhibits unique and recognizable signs on CT and MRI.
- Early detection through imaging facilitates effective treatment.
- Untreated PRES can lead to ischemic stroke, infarction, and mortality.
Conclusions:
- Radiologists play a key role in the early diagnosis of PRES.
- Recognizing specific imaging patterns is essential for prompt management.
- Timely treatment of PRES can prevent severe neurological damage and improve patient outcomes.

