Related Experiment Video
Updated: Mar 8, 2026
09:14
Surgical Approach to Full Soft Tissue Face Allograft Procurement for Vascularized Composite Allotransplantation
Published on: December 30, 2025
150
The first sixty-five craniopharyngioma operations in France
I Castro-Dufourny1, R Carrasco2, R Prieto3
1Department of Endocrinology, Sureste University Hospital, C/Ronda del Sur 10, Arganda del Rey, 28500 Madrid, Spain.
Revue Neurologique
|January 30, 2017
Summary
Early craniopharyngioma (CP) surgical management, particularly before advanced neuroradiology, often resulted in poor outcomes. Preoperative assessment of hypothalamic involvement is crucial for improving surgical results in CP patients today.
Area of Science:
- Neurosurgery
- Neuroendocrinology
- Oncology
Background:
- Craniopharyngiomas (CPs) are benign epithelial tumors arising along the hypothalamus-hypophyseal axis.
- Their surgical management has historically presented significant challenges.
- The study of CPs is intertwined with the evolution of neurosurgery and neuroendocrinology.
Observation:
- This study analyzed 65 surgically treated craniopharyngioma cases from French literature predating modern neuroradiology (1921-1973).
- Adamantinomatous CPs in the infundibulo-tuberal region were most common.
- Subfrontal surgical approaches were most frequent.
Findings:
- Surgical approach and extent of resection were not consistently guided by tumor topography.
- Nearly half (47%) of patients experienced poor surgical outcomes.
- Hypothalamic and/or infundibular damage, indicated by symptoms like infundibulo-tuberal syndrome, was recognizable.
Implications:
- Historical CP case reviews offer insights into current surgical strategies.
- Accurate preoperative assessment of hypothalamic involvement is vital for optimizing surgical outcomes.
- Debate continues regarding optimal surgical approaches and resection degrees for craniopharyngiomas.
