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Updated: Aug 19, 2026

Stabilizing Hepatocellular Phenotype Using Optimized Synthetic Surfaces
Published on: September 26, 2014
[Polysorbates for hemoperfusion. The effect of polysorbate surface modification on morphology, coagulation,
M Kotschy1, P Jurkowski, E Zekanowska
1Katedra i Zakład Patofizjologii Akademii Medycznej w Bydgoszczy.
Abstract:
In the work the influence of surface sulfonated polymer sorbents with styrene-divinylbenzene (Vinylsorb SS) modified by amino acids upon the morphological picture of blood and proteins of the coagulation system was tested. Those sorbents do not exert a remarkable influence upon erythrocytes and coagulation proteins but they adsorb blood platelets, leucocytes and they activate prekallikrein system. Vinylsorb SS has the best influence because it adsorbs few platelets and activates prekallikrein system to the least extent.
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