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Author Spotlight: Optimizing CFU Determination for Efficient Assessment of TB Vaccine Efficacy and Antigen Presentation Analysis
Published on: July 28, 2023
R&D in Vaccines Targeting Neglected Diseases: An Exploratory Case Study Considering Funding for Preventive
Theolis Costa Barbosa Bessa1, Erika Santos de Aragão2, Jane Mary Medeiros Guimarães3
1Gonçalo Moniz Institute, Oswaldo Cruz Foundation Unit in Bahia State, Rio de Janeiro, RJ, Brazil.
Abstract:
Based on an exploratory case study regarding the types of institutions funding the research and development to obtain new tuberculosis vaccines, this article intends to provoke discussion regarding the provision of new vaccines targeting neglected disease. Although our findings and discussion are mainly relevant to the case presented here, some aspects are more generally applicable, especially regarding the dynamics of development in vaccines to prevent neglected diseases. Taking into account the dynamics of innovation currently seen at work in the vaccine sector, a highly concentrated market dominated by few multinational pharmaceutical companies, we feel that global PDP models can play an important role throughout the vaccine development cycle. In addition, the authors call attention to issues surrounding the coordination of actors and resources in the research, development, manufacturing, and distribution processes of vaccine products arising from PDP involvement.
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