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Related Concept Videos

Papillary Dermis01:11

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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
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The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Desmosomes

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The term desmosome derives from the Greek words "desmo" and "soma" meaning "adhesion bodies." This structure was first observed during the late 1800s and described as small, dense nodules in the epidermis. Desmosomes are button-like structures that help form an interlinked network of intermediate filaments across the cells. These junctions are  essential to hold cells together under mechanical stress and to maintain tissue integrity. Desmosomes are multi-protein...
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Elastin is Responsible for Tissue Elasticity01:12

Elastin is Responsible for Tissue Elasticity

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Elastic fiber contains the protein elastin along with lesser amounts of other proteins and glycoproteins. The main property of elastin is that it will return to its original shape after being stretched or compressed. Elastic fibers are prominent in elastic tissues found in skin and the elastic ligaments of the vertebral column.
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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Papillary Dermal Elastosis.

José Fernando Val-Bernal1, María Carmen González-Vela, Alicia León-Castillo

  • 1*Pathology Unit, Medical and Surgical Sciences Department, University of Cantabria and IDIVAL, Santander, Spain; †Anatomical Pathology Service, Marqués de Valdecilla University Hospital, Medical Faculty, University of Cantabria and IDIVAl, Santander, Spain; and ‡Dermatology Service, Marqués de Valdecilla University Hospital, Medical Faculty, University of Cantabria and IDIVAL, Santander, Spain.

The American Journal of Dermatopathology
|January 31, 2017
PubMed
Summary
This summary is machine-generated.

Papillary dermal elastosis is a rare skin condition. This case report confirms the entity and aids understanding of fibroelastolytic disorders.

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Area of Science:

  • Dermatopathology
  • Histology
  • Dermatology

Background:

  • Papillary dermal elastosis is an exceptionally rare clinicopathological finding.
  • Only one previous case has been documented in medical literature.

Observation:

  • A 38-year-old woman presented with a 10-month history of pruritic, nonfollicular papules on her back.
  • The papules were 1-2 mm in size and slowly progressive.

Findings:

  • Histopathological examination revealed increased elastosis in the dermal papillae.
  • Verhoeff elastic staining highlighted clumped and curled elastic fibers within the papillary dermis.
  • The reticular dermis showed a normal elastic component.

Implications:

  • This case report reinforces the existence of papillary dermal elastosis.
  • It contributes to the understanding of the spectrum of fibroelastolytic conditions.
  • Further research may elucidate the pathogenesis and clinical behavior of this rare entity.