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Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

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Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
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Other Pulmonary Disorders01:17

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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
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The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
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Updated: Mar 8, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
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Obstructive Sleep Apnea and Perinatal Risk.

Margarita Reyes-Zúñiga1, Luis Torre-Bouscoulet1

  • 1Sleep Clinic, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City, Mexico.

Revista De Investigacion Clinica; Organo Del Hospital De Enfermedades De La Nutricion
|January 31, 2017
PubMed
Summary
This summary is machine-generated.

Obstructive sleep apnea during pregnancy is linked to increased risks for mothers and babies. Treating this condition may reduce maternal and perinatal complications.

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Area of Science:

  • Obstetrics and Gynecology
  • Sleep Medicine
  • Cardiology

Background:

  • Obstructive sleep apnea (OSA) involves repeated upper airway obstructions during sleep, leading to systemic inflammation and endothelial dysfunction.
  • Pregnancy is associated with a higher prevalence of OSA, particularly in the third trimester.
  • OSA is an independent risk factor for adverse maternal and perinatal outcomes, including low birth weight.

Purpose of the Study:

  • To review the current evidence on the association between obstructive sleep apnea and maternal/perinatal risks.
  • To explore the role of endothelial dysfunction as a potential mechanism linking OSA to adverse perinatal outcomes.
  • To evaluate the potential benefits of treating OSA in pregnancy.

Main Methods:

  • Review of experimental and prospective human studies.
  • Analysis of the impact of OSA on endothelial function.
  • Examination of the association between OSA and perinatal morbidity/mortality.

Main Results:

  • Obstructive sleep apnea is linked to increased risks of cardiometabolic events due to endothelial dysfunction.
  • Studies show a correlation between OSA and low birth weight.
  • Evidence suggests OSA is a modifiable risk factor for maternal and perinatal complications.

Conclusions:

  • Endothelial dysfunction may mediate the link between OSA and high perinatal risk.
  • Treating obstructive sleep apnea with positive airway pressure devices may decrease maternal and perinatal morbidity and mortality.
  • OSA management is a potential strategy to improve pregnancy outcomes.