Related Experiment Video
Updated: Mar 8, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Predictive Validity of a Screening Instrument for the Risk of Non-Return to Work in Patients With Internal Diseases
Marco Streibelt1, Matthias Bethge2, Thomas Gross3
1Department of Rehabilitation, German Federal Pension Insurance, Berlin, Germany.
The Screening Instrument for the Access to Work-Related Multimodal Rehabilitation (SIMBO) score effectively predicts return-to-work challenges in patients with internal diseases post-rehabilitation. A score of 27 is a reliable threshold for identifying these risks.
Area of Science:
- Rehabilitation Medicine
- Occupational Health
- Health Services Research
Background:
- Assessing work-related outcomes is crucial for patients undergoing medical rehabilitation.
- Predictive tools are needed to identify individuals at risk of return-to-work (RTW) difficulties.
- The SIMBO score's validity for internal diseases requires further investigation.
Purpose of the Study:
- To evaluate the predictive accuracy of the SIMBO score for return-to-work in patients with internal diseases.
- To determine the effectiveness of the SIMBO score in a real-world rehabilitation setting.
- To validate the established cutoff score of 27 for risk stratification.
Main Methods:
- Prospective, multicenter study involving 1366 patients (aged 18-65) with internal diseases.
- Patients received multimodal rehabilitation programs.
- Primary outcome: critical RTW event within a 3-month follow-up period. ROC analyses were used to assess predictive validity.
Main Results:
- The SIMBO score demonstrated strong predictive validity across various internal disease groups (neoplasms, endocrine, circulatory, respiratory, digestive).
- Area under the curve values ranged from .849 to .903, indicating good discriminative ability.
- Sensitivity and specificity were high, ranging from 65.6%–92.9% and 80.4%–89.9%, respectively.
Conclusions:
- The SIMBO score is a valid tool for predicting short-term return-to-work problems in patients with internal diseases after rehabilitation.
- The cutoff score of 27 points is confirmed as an appropriate threshold for identifying patients at risk.
- Findings support the use of SIMBO in clinical practice for targeted RTW interventions.
More Related Videos
07:31Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
Published on: May 15, 2020
06:28E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
Published on: August 1, 2019
Related Concept Videos
Sensitivity, Specificity, and Predicted Value
Sensitivity is the...
Receiver Operating Characteristic Plot