Long term treatment with oxaprotiline in patients with major depression

1) Four hundred thirty-seven patients with depressive illness were treated for up to 11 months with oxaprotiline (Ba-49802B) in a continuation study. 2) Results of this study suggest that oxaprotiline continued to be effective in alleviating depressive symptoms. 3) Additionally, evaluation of safety parameters failed to reveal any significant risk to patients who were treated with oxaprotiline over this extended period of time.