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Acoustic radiation force impulse imaging of kidneys - a phantom study
Szymon Cygan1, Magdalena Januszewicz2
1Institute of Metrology and Biomedical Engineering, Warsaw University of Technology, Warsaw, Poland.
Journal of Ultrasonography
|February 1, 2017
Summary
Acoustic Radiation Force Impulse (ARFI) imaging is reliable for kidney diagnosis when measurements are in uniform tissue. Non-uniform tissue regions can affect results, but measurement variance remains consistent regardless of depth or uniformity.
Area of Science:
- Medical Imaging
- Biophysics
- Ultrasound Technology
Background:
- Limited studies exist on Acoustic Radiation Force Impulse (ARFI) for kidney diagnosis.
- Existing research shows inconsistent shear wave velocity (SWV) measurements in renal tissue.
- Kidney phantoms offer a controlled environment to assess ARFI reliability.
Purpose of the Study:
- To evaluate the reliability of the ARFI technique for kidney examination.
- To assess SWV measurement consistency in a controlled phantom setup.
- To understand factors influencing ARFI accuracy in simulated renal tissue.
Main Methods:
- Manufactured four gelatin-based kidney phantoms simulating varying cortical thickness and patient depths.
- Utilized Siemens Acuson S2000 ultrasound with a 6C1 HD Transducer.
- Performed 20 Shear Wave Velocity (SWV) measurements at multiple points per phantom using Virtual Touch Tissue Quantification™.
Main Results:
- Mean SWV values ranged from 2.445 to 3.941 m/s across all measurements.
- Standard deviation exceeded 0.1 in only one of 29 points, indicating high precision.
- Significant differences in SWV were observed between measurement points.
Conclusions:
- ARFI is highly reliable for kidney assessment when measurement volumes are uniform.
- Partial inclusion of non-uniform tissue regions significantly affects SWV results.
- Measurement variance is independent of tissue uniformity and measurement depth.
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