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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Related Experiment Video

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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
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A New Glaucoma Severity Score Combining Structural and Functional Defects.

J Wachtl1, M Töteberg-Harms1, S Frimmel1

  • 1University Hospital Zurich, Department of Ophthalmology, Zurich, Switzerland.

Klinische Monatsblatter Fur Augenheilkunde
|February 1, 2017
PubMed
Summary
This summary is machine-generated.

A new Glaucoma Severity Score (GSS) objectively assesses glaucoma by combining structural and functional eye data. This user-friendly tool enables consistent patient and study comparisons for glaucoma progression.

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Area of Science:

  • Ophthalmology
  • Medical Technology
  • Clinical Assessment

Background:

  • Glaucoma staging lacks a universally accepted, objective standard.
  • Accurate assessment requires integrating structural and functional testing data.
  • Need for a tool to compare glaucoma severity across patients and studies.

Purpose of the Study:

  • To develop and validate the Glaucoma Severity Score (GSS).
  • GSS combines Retinal Nerve Fibre Layer (RNFL) thickness, perimetric mean defect (MD), and anatomical-perimetric agreement.
  • To provide an objective measure for glaucoma severity assessment.

Main Methods:

  • Developed a staging tool for RNFL thickness, MD, and defect agreement.
  • Glaucoma specialists assigned scores (0-2 or 0-3) based on consensus criteria.
  • Prospective observational study of 112 glaucoma patients assessed using the GSS.

Main Results:

  • The Glaucoma Severity Score (GSS) was applied to 112 patients.
  • Mean GSS was 4.73 points.
  • High inter-rater agreement (Cohen's kappa = 0.83) confirmed objectivity of criteria.

Conclusions:

  • The Glaucoma Severity Score (GSS) is an objective, user-friendly tool for glaucoma staging.
  • GSS facilitates comparison of glaucoma severity across patients and studies.
  • Further validation against existing tools like FORUM® Glaucoma Workplace is planned.