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Updated: Mar 8, 2026

Studying Chronic Exposure of Mice to Ultraviolet B Radiation
Published on: August 19, 2025
Can Puva Darken Grey Hair
UV radiation and psoralen treatment did not darken premature grey hairs. This study investigated the effects of ultraviolet A (UVA) and ultraviolet B (UVB) light, with and without psoralen, on hair color change.
Area of Science:
- Dermatology
- Photobiology
- Hair Science
Background:
- Premature graying of hair is a common concern.
- The effects of ultraviolet (UV) radiation on hair pigmentation are not fully understood.
Purpose of the Study:
- To investigate whether UVA or UVB radiation can induce darkening of premature grey hairs.
- To determine if psoralen combined with UVA radiation can alter the color of grey hairs.
Main Methods:
- Grey hairs from patients with premature graying were collected.
- Hairs were exposed daily to UVA or UVB radiation for 30 minutes over 17 days.
- A separate group of hairs was treated with a 1% aqueous psoralen solution before daily UVA exposure for 17 days.
Main Results:
- Neither UVA nor UVB radiation alone caused any darkening of the grey hairs.
- The combination of psoralen treatment and UVA exposure did not result in hair darkening.
Conclusions:
- UV radiation, with or without psoralen, does not appear to reverse or induce pigmentation in prematurely grey human hairs.
- Further research may be needed to explore other potential treatments for hair repigmentation.
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