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Updated: Mar 8, 2026
Characterization of Cell Membrane Extensions and Studying Their Roles in Cancer Cell Adhesion Dynamics
Published on: March 26, 2018
Fractal Analysis of Cancer Cell Surface
Igor Sokolov1,2,3, Maxim E Dokukin4
1Department of Mechanical Engineering, Tufts University, 177 College Ave., Medford, MA, 02155, USA. Igor.sokolov@tufts.edu.
Abstract:
Fractal analysis of the cell surface is a rather sensitive method which has been recently introduced to characterize cell progression toward cancer. The surface of fixed and freeze-dried cells is imaged with atomic force microscopy (AFM) modality in ambient conditions. Here we describe the method to perform the fractal analysis specifically developed for the AFM images. Technical details, potential difficulties, points of special attention are described.
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