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Navigating the Mass Spectrometry-Based Proteomic Data Using Free Computational Tools
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Bioinformatics Analysis of Top-Down Mass Spectrometry Data with ProSight Lite

Caroline J DeHart1, Ryan T Fellers1, Luca Fornelli1

  • 1Departments of Chemistry, Molecular Biosciences, the Proteomics Center of Excellence and the Robert H. Lurie Comprehensive Cancer Center at the Feinberg School of Medicine, Northwestern University, Evanston, IL, 60208, USA.

Methods in Molecular Biology (Clifton, N.J.)
|February 3, 2017
PubMed
Summary

Top-down mass spectrometry analyzes intact proteins, offering a simpler approach than traditional methods. This study demonstrates using ProSight Lite software for analyzing these complex protein spectra to identify modifications.

Keywords:
BioinformaticsIntact proteinMass spectrometryProSight LiteProteomicsTop-down

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