Liver transplantation around the world

Area of Science:

• Hepatology
• Transplantation Surgery
• Global Health

Background:

• Significant global shifts in liver transplantation development have occurred recently.
• Emerging countries show rapid growth in transplant programs.
• Key changes include liver allocation, donation after cardiac death, and living donor utilization.

Purpose of the Study:

• To review and compare international liver transplantation practices.
• To provide insights for improving local transplant programs.
• To foster learning from global colleagues' experiences.

Main Methods:

• A review of recent articles published in "Liver Transplantation" journal.
• Summarization of liver transplantation practices from representative countries worldwide.

Main Results:

• Liver transplant volumes differ significantly across countries, with notable growth in emerging economies.
• The Model for End-Stage Liver Disease (MELD) score is the primary prioritization tool, with most transplants occurring at MELD scores of 18-20 (except in Germany and the USA).
• Hepatitis C is a leading indication for liver transplantation, though less so in some European nations. Innovative donation incentive strategies are emerging globally.

Conclusions:

• International collaboration and knowledge sharing are crucial for advancing liver transplantation.
• Understanding global trends can identify areas for improvement in transplant programs worldwide.
• Emerging countries are increasingly contributing to the global liver transplant landscape.