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Bronchial mucoepidermoid carcinoma: A case report
Alessandro G Fois1, Gabriella Diana1, Antonella Arcadu1
1Respiratory Disease Institute, Department of Clinical and Experimental Medicine, University of Sassari, Viale San Pietro 43, 07100, Sassari, Italy.
International Journal of Surgery Case Reports
|February 3, 2017
Summary
Bronchial mucoepidermoid carcinoma (MEC) is rare. This case highlights successful surgical management and excellent prognosis for low-grade bronchial MEC.
Area of Science:
- Pulmonology
- Oncology
- Pathology
Background:
- Bronchial mucoepidermoid carcinoma (MEC) is an uncommon lung neoplasm.
- Limited understanding exists regarding the histogenesis and pathogenesis of bronchial MEC.
- This study presents a detailed pathological, immunohistochemical, and molecular analysis of a rare bronchial MEC case.
Purpose of the Study:
- To present a detailed case study of bronchial mucoepidermoid carcinoma.
- To analyze the pathological, immunohistochemical, and molecular characteristics of the tumor.
- To discuss the clinical management and prognosis of low-grade bronchial MEC.
Main Methods:
- A 46-year-old male presented with symptoms of cough and dyspnea.
- Chest CT revealed an 8-mm intraluminal bronchial lesion.
- Diagnosis was confirmed via bronchoscopic biopsies, followed by left upper lobectomy and histopathological staging (pT1N0M0).
Main Results:
- Histopathology confirmed a low-grade mucoepidermoid carcinoma of the lung.
- The patient underwent successful surgical resection (left upper lobectomy).
- The patient remains disease-free for three years post-surgery, indicating an excellent prognosis for this stage and grade.
Conclusions:
- Low-grade bronchial MEC, as demonstrated in this case, typically has an optimal clinical management and prognosis with surgical resection.
- Surgical treatment aims for complete tumor removal (R0 resection).
- While high-grade tumors can be aggressive, low-grade MECs show favorable outcomes, and targeted therapies may benefit non-responsive patients.

