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Necrotizing Enterocolitis and Human Milk Feeding: A Systematic Review
Nicole Theresa Cacho1, Leslie A Parker2, Josef Neu3
1Division of Neonatology, Department of Pediatrics, University of Florida, 1600 Southwest Archer Road, HD-118, Gainesville, FL 32610, USA.
Clinics in Perinatology
|February 5, 2017
Summary
Donor human milk (DHM) and exclusively human milk (EHM) may reduce necrotizing enterocolitis (NEC) risk in premature infants. Further research is needed to confirm protection and determine optimal human milk (HM) doses for NEC prevention.
Area of Science:
- Neonatal nutrition
- Gastroenterology
- Pediatric research
Background:
- Necrotizing enterocolitis (NEC) is a serious gastrointestinal condition affecting premature infants.
- Human milk (HM) is known to protect against NEC, but optimal feeding strategies require further investigation.
Purpose of the Study:
- To summarize evidence on whether donor human milk (DHM) and/or exclusively human milk (EHM) diets reduce NEC incidence in premature infants.
- To identify the necessary dose of human milk (HM) for NEC risk reduction.
Main Methods:
- Literature review and evidence synthesis.
- Analysis of existing research on human milk feeding and NEC outcomes in preterm neonates.
Main Results:
- Evidence suggests DHM and EHM may decrease NEC incidence.
- The precise dose of HM required for NEC risk reduction remains to be fully elucidated.
Conclusions:
- Additional research is necessary to confirm the protective effects of DHM and EHM against NEC.
- Further studies are needed to determine optimal HM dosing strategies and investigate potential dose-dependent effects for NEC prevention.
