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A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
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Incidence, Frequency, and Clinical Characteristics of Type 3 Myocardial Infarction in Clinical Practice

Nikolaj Jangaard1, Laura Sarkisian1, Lotte Saaby1

  • 1Department of Cardiology, Odense University Hospital, Denmark.

The American Journal of Medicine
|February 5, 2017
PubMed

Insights

Type 3 myocardial infarction, a cardiac death without biomarker evidence, is rare. This study found an annual incidence of 7.3 per 100,000 person-years, representing 3.6% of all myocardial infarctions.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Type 3 myocardial infarction is defined as cardiac death with ischemic symptoms and ECG changes but no biomarker data.
  • Understanding the incidence and characteristics of Type 3 myocardial infarction is crucial for accurate diagnosis and public health assessment.

Purpose of the Study:

  • To investigate the incidence, frequency, and patient characteristics of Type 3 myocardial infarction.

Main Methods:

  • Data on deaths were collected from the Danish Civil Registration System (2010-2011).
  • Causes of death were verified using the Danish Register of Causes of Death and patient files.
  • Diagnosis of Type 3 myocardial infarction was adjudicated by expert cardiologists.

Main Results:

  • 18 cases of Type 3 myocardial infarction were identified, yielding an annual incidence of 7.3 per 100,000 person-years.
  • Type 3 myocardial infarction accounted for 3.6% of all myocardial infarctions (18 of 506).
  • The overall mortality in the region was 2766 out of 246,723 adult residents.

Conclusions:

  • Type 3 myocardial infarction is a rare event, with an incidence below 10 per 100,000 person-years and a frequency of 3%-4% among all myocardial infarctions.
  • Inclusion of autopsy data may increase the observed number of Type 3 myocardial infarction cases.
Abstract

Keywords:
Mortality/survivalQuality and outcomesResource utilizationSyncope

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