Cardiovascular burden and percutaneous interventions in Russian Federation: systematic epidemiological update

Area of Science:

• Epidemiology
• Public Health
• Cardiology

Background:

• High cardiovascular (CV) mortality and shorter lifespans in Russia compared to Western societies.
• Absence of established monitoring or screening systems for major CV risk factors.
• CV diseases account for a significant portion of all deaths in Russia.

Purpose of the Study:

• To conduct a systematic epidemiological update on the CV burden in Russia.
• To explore trends in CV burden across all 83 regions of Russia.
• To identify major modifiable risk factors contributing to CV diseases.

Main Methods:

• Systematic epidemiological review of national mass screenings, randomized clinical trials, and statistical datasets.
• Analysis of Russian-speaking national data sources from 2001-2014.
• Inclusion of the NANOM-FIM trial (NCT01270139) as a real-world population study.

Main Results:

• Cardiovascular diseases accounted for 54.9% of all deaths (2011-2014).
• Major modifiable risk factors include smoking, excessive alcohol consumption, unhealthy diet, psychosocial factors, and physical inactivity.
• High prevalence of dyslipidemia (86.7%), obesity (16.7%), and hypertension (40.8% to 86.1%) observed.

Conclusions:

• Despite a documented 27% 10-year decline in CV mortality, the CV burden in Russia remains high.
• New national programs and aggressive efforts are required to tackle CV diseases.
• Mortality statistics highlight the urgent need for interventions to reduce CV disease impact.