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An Unusual Symmetrical Fixed Drug Eruption.
Indian Journal of Dermatology, Venereology and Leprology
|February 7, 2017
Summary
A rare case of fixed drug eruption, a skin reaction to medication, presented with a unique symmetrical pattern on the hands and feet. This finding highlights the varied clinical presentations of fixed drug eruptions.
Area of Science:
- Dermatology
- Clinical Case Reports
- Adverse Drug Reactions
Background:
- Fixed drug eruption (FDE) is an idiosyncratic cutaneous reaction to a medication, typically presenting with recurrent, well-demarcated erythematous to violaceous plaques at specific sites upon re-exposure.
- Commonly affected sites include the genitalia, trunk, and limbs, but symmetrical distribution on the hands and feet is infrequent.
Observation:
- This report details an unusual case of fixed drug eruption in a patient exhibiting a distinct symmetrical distribution of lesions on both hands and feet.
- The lesions appeared consistently on these symmetrical locations following exposure to the causative agent.
Findings:
- The symmetrical presentation on the hands and feet represents an atypical pattern for fixed drug eruption.
- Diagnostic confirmation was based on clinical presentation and patient history of recurrent lesions at these specific sites after drug intake.
Implications:
- This case expands the spectrum of clinical manifestations of fixed drug eruption.
- Awareness of such unusual distributions is crucial for timely diagnosis and appropriate management of fixed drug eruption, preventing further adverse reactions.