Topical Ciclopirox Olamine 1%: Revisiting a Unique Antifungal

Sidharth Sonthalia1, Mahima Agrawal2, V N Sehgal3

  • 1Department of Dermatology and Dermatosurgery, Skinnocence, The Skin Clinic and Research Centre, Gurugram, Haryana, India.

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Second Uniqueness Theorem01:16

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SN1 Reaction: Kinetics02:05

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Acidity of 1-Alkynes02:42

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The acidic strength of hydrocarbons follows the order: Alkynes > Alkenes > Alkanes. The strength of an acid is commonly expressed in units of pKa — the lower the pKa, the stronger the acid. Among the hydrocarbons, terminal alkynes have lower pKa values and are, therefore, more acidic. For example, the pKa values for ethane, ethene, and acetylene are 51, 44, and 25, respectively, as shown here.
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