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Malaria treatment using novel nano-based drug delivery systems
Uday Krishna Baruah1, Kuppusamy Gowthamarajan1, Ravisankar Vanka1
1a Department of Pharmaceutics , JSS College of Pharmacy, Ootacamund, JSS University , Mysuru , India.
Journal of Drug Targeting
|February 7, 2017
Summary
Malaria remains a global threat due to drug resistance and toxicity. Nano-based drug delivery systems offer a promising solution for targeted malaria treatment, minimizing resistance and side effects.
Area of Science:
- Medical research
- Nanotechnology
- Infectious diseases
Background:
- Malaria continues to be a significant global health threat, causing high mortality rates.
- Current antimalarial therapies face challenges including drug resistance and nonspecific targeting.
- Dose-related toxicity of existing drugs is a major concern in malaria treatment.
Purpose of the Study:
- To review the limitations of current malaria treatment strategies.
- To explore the potential of nano-based drug delivery systems in combating malaria.
- To highlight how nanotechnology can improve malaria therapy efficacy and safety.
Main Methods:
- Literature review of existing studies on malaria treatment.
- Analysis of shortcomings in conventional antimalarial drug delivery.
- Investigation of nano-based drug delivery systems for targeted therapy.
Main Results:
- Nano-based systems can facilitate site-specific drug delivery for malaria.
- Targeted delivery minimizes the development of drug resistance.
- Reduced toxicity is achieved by lowering effective drug doses.
Conclusions:
- Nano-based drug delivery presents a viable strategy to overcome challenges in malaria treatment.
- This approach holds promise for reducing mortality and morbidity associated with malaria.
- Further research and development in nanomedicine are crucial for effective malaria control.
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