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Updated: Mar 7, 2026

Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing
Published on: December 23, 2022
Emerging pathogens in the fish farming industry and sequencing-based pathogen discovery
Torstein Tengs1, Espen Rimstad2
1Department of Chemistry, Biotechnology and Food Sciences, Faculty of Veterinary Medicine and Biosciences, Norwegian University of Life Sciences, 1430 Aas, Norway.
Large-scale DNA/RNA sequencing revolutionizes biomedical research, enabling advanced pathogen discovery. This review highlights progress in identifying emerging viruses in Atlantic salmon using sequence data.
Area of Science:
- Biomedical Research
- Genomics
- Pathogen Discovery
Background:
- Large-scale DNA/RNA sequencing is now fundamental in biomedical research.
- Decreased sequencing costs and enhanced computational power drive innovation in genomics and transcriptomics.
- Emerging pathogens pose risks to human and animal health, influenced by globalization and environmental changes.
Purpose of the Study:
- To review recent advancements in pathogen discovery utilizing sequence data.
- To focus on the identification of viruses affecting Atlantic salmon (Salmo salar).
Main Methods:
- Utilizing large-scale DNA/RNA sequencing for pathogen identification.
- Analyzing genomic and transcriptomic data for novel viral detection.
Main Results:
- Sequence-based methods have made previously infeasible pathogen discovery possible.
- Fish farming systems present unique challenges for studying emerging pathogens.
Conclusions:
- Sequence data analysis is a powerful tool for identifying emerging pathogens, particularly viruses in aquaculture.
- Continued research is vital for understanding and mitigating viral threats in farmed fish populations.
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