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Related Experiment Video

Updated: Mar 7, 2026

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice

Published on: January 12, 2017

Evaluation of indirect pulp capping using three different materials: A randomized control trial using cone-beam

Vijay Prakash Mathur¹, Jatinder Kaur Dhillon², Ajay Logani¹

¹Center for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India.

Indian Journal of Dental Research : Official Publication of Indian Society for Dental Research

|February 8, 2017

Summary

This study found calcium hydroxide, glass ionomer cement, and mineral trioxide aggregate to be equally effective for indirect pulp treatment in children. All materials promoted reparative dentin formation, ensuring successful pulp capping.

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Published on: March 7, 2014

Area of Science:

Pediatric Dentistry
Dental Materials Science
Radiology

Background:

Indirect pulp treatment (IPT) is crucial for preserving deep carious lesions in primary and permanent teeth.
Evaluating the clinical efficacy and hard tissue response of different materials used in IPT is essential.

Purpose of the Study:

To determine the most suitable material for indirect pulp treatment (IPT) in children.
To assess the thickness and radiodensity of reparative dentin formed after pulp capping using cone-beam computed tomography (CBCT).

Main Methods:

A single-blind randomized clinical trial involving 94 children (7-12 years) and 109 teeth.
Teeth were treated with calcium hydroxide, glass ionomer cement, or mineral trioxide aggregate for IPT.
Success was evaluated using American Academy of Pediatric Dentistry criteria, with CBCT scans for dentin bridge assessment.

Main Results:

The overall success rate for indirect pulp capping (IPC) was 96.85%.
Significant differences in reparative dentin thickness and radiodensity (Hounsfield units) were observed between immediate and 6-month postoperative CBCT scans across all material groups.
All three tested materials demonstrated comparable efficacy in forming a distinct barrier.

Conclusions:

Calcium hydroxide, glass ionomer cement, and mineral trioxide aggregate are equally suitable for indirect pulp treatment.
The study confirms the formation of a mineralized barrier, indicating successful IPT and mineral gain.
CBCT is a valuable tool for evaluating dentin bridge formation in terms of thickness and radiodensity.