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Updated: Mar 7, 2026
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Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting
Published on: June 21, 2024
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[Persistent Chemotherapy-Induced Hiccups Successfully Treated with Pregabalin]
Kyoko Nakanishi1, Kumi Sugiyama, Yasushi Abe
1Dept. of Palliative Care, Asahikawa Medical University Hospital [Currently Dept. of Palliative Care, Asahikawa-Kosei General Hospital].
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|February 9, 2017
Summary
This study explores a potential treatment for persistent hiccups caused by chemotherapy. Pregabalin effectively resolved hiccups in a lung cancer patient, allowing uninterrupted treatment.
Area of Science:
- Oncology
- Pharmacology
- Neurology
Background:
- Large cell lung cancer (c-Stage IV) diagnosis in a 62-year-old male.
- Chemotherapy regimen included cisplatin, pemetrexed, and bevacizumab.
Observation:
- Patient developed persistent hiccups on day 2 of chemotherapy.
- Previous treatments (chlorpromazine, shakuyakukanzoto, gabapentin) were ineffective.
Findings:
- Immediate resolution of hiccups upon administration of pregabalin.
- Successful completion of 4 chemotherapy courses with pregabalin prophylaxis.
Implications:
- Pregabalin shows promise as a therapeutic option for chemotherapy-induced hiccups.
- This finding could improve patient tolerance and adherence to cancer treatment regimens.
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